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       Zhang Y., Proenca R., Maffei M., Barone M., Leopold L and Friedman J. Positional Cloning of the mouse obese  gene and its human homologue. Nature, 372: 425-432. (1994) 

        Maffei M., Fei H., Lee G.W., Dani C., Leroy P., Zhang Y., Proenca R., Negrel R., Ailhaud G., and Friedman J. Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db  locus. Proc. Nat. Acad. Sci. USA, 92: 6957-6960 (1995). 

       Halaas J.L., Gajiwala K. S.,  Maffei M., Cohen S.L., Chait B.T.,  Rabinowitz D., Lallone R.L., Burley S.K., and Friedman J.M. Weight Reducing Effects of the Plasma Protein Encoded by the obese  Gene. Science , 269:  543-546. (1995). 

        Maffei M.,  Stoffel M.,  Barone M., Moon B.,  Ravussin E.,  Bogardus C.,  Ludwig D.,  Flier J.,  Talley M., Auerbach S. and  Friedman J.F. Abscence of  Mutations in  the Human Ob  Gene  in Obese/Diabetic Subjects. Diabetes , 45: (1996) 

         Birsoy K , Soukas A,  Torrens J, Ceccarini G, Montez J, Maffei M, Cohen P, Fayzikhodjaeva  G, Viale A, Socci N Friedman J. The cellular program controlling the recovery of adipose tissue mass-an in vivo imaging approach. Proc. Nat. Acad. Sci. USA, 105: 12985-90. (2008) 

      Ceccarini G, Flavell RR, Butelman ER, Synan M, Willnow TE, Bar-Dagan M, Goldsmith SJ, Kreek MJ, Kothari P, Vallabhajosula S, Muir TW, Friedman JM. “PET Imaging of Leptin Biodistribution and Metabolism in Rodents and Primates” Cell Metabolism (10), 148-159,  2009.

      Ceccarini G, Ribeiro AC, Dupré C, Friedman JM, Pfaff DW, Mark AL. “Opposing effects of leptin on food anticipatory and total locomotor activities in leptin deficient obese mice” . PLoS One. 2011;6(8):e23364.

       Mainardi M, Scabia G, Vottari T, Santini F, Pinchera A, Maffei L, Pizzorusso T, Maffei M. A sensitive period for environmental regulation of eating behavior and leptin sensitivity.  Proc Natl Acad Sci U S A. 2010;107):16673-8.  (2010).

      Pelosini C, Martinelli S, Bagattini B, Pucci E, Fierabracci P, Scartabelli G, Salvetti G, Vitti P, Maffei M, Pinchera A, Santini F Description of an AGPAT2 pathologic allelic variant in a 54-year-old Caucasian woman with Berardinelli-Seip syndrome. Acta Diabetol., 48: 243-6  2011

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